Layne Norton

An adaptogen with real RCT data for stress and cortisol reduction — not Grade A because trial sizes are small and long-term data is limited.

An amino acid that raises muscle carnosine and consistently improves performance in high-intensity exercise lasting 1-4 minutes.

A methyl donor with solid evidence for lowering homocysteine and moderate evidence for improving power output during resistance training — but not body composition.

An amino acid that boosts nitric oxide production — good evidence for improving exercise performance and blood flow, though effect sizes are moderate and study quality varies.

Hydrolyzed collagen with growing RCT evidence for skin elasticity and joint comfort, though the effect sizes are modest and the mechanisms are still debated.

The most-studied sports supplement in history — strong evidence for strength and power, emerging evidence for cognitive benefits.

The body's most abundant amino acid with strong evidence for gut barrier integrity and immune support in stressed populations, but less clear benefit for healthy people.

A foundational mineral most people under-consume — strong for correcting inadequacy, modest (not magical) for sleep.

The most well-studied sleep supplement with strong evidence for sleep onset and jet lag — but effective at much lower doses than commonly sold.

An adaptogenic herb with solid RCT evidence for reducing mental fatigue and improving stress resilience, particularly under demanding conditions.

A conditionally essential amino acid with solid evidence for cardiovascular protection and emerging longevity interest, though human lifespan data is still absent.

The most-studied protein supplement — strong and consistent evidence for supporting muscle protein synthesis, recovery, and lean mass gains when combined with resistance training.