Skin & Anti-Aging

A well-established antioxidant essential for immune function, collagen synthesis, and iron absorption — evidence supports modest immune benefits, especially under physical stress.

Hydrolyzed collagen with growing RCT evidence for skin elasticity and joint comfort, though the effect sizes are modest and the mechanisms are still debated.

Infrared saunas show meaningful cardiovascular and recovery benefits, with emerging but less conclusive evidence for detoxification and skin health.

A well-studied flavonoid with decent anti-inflammatory and immune evidence, plus emerging interest as a senolytic when paired with dasatinib.

Red light therapy (photobiomodulation) has growing RCT support for skin health and exercise recovery, though optimal protocols are still being defined.

An essential fat-soluble vitamin for vision, immune function, and skin integrity — most people get enough from food, but deficiency remains a global health concern.

A fat-soluble antioxidant that protects cell membranes — essential from food, but supplementation evidence is mixed and high doses may carry risk.

A senolytic flavonoid with striking mouse data on clearing senescent cells, but human clinical trials are only just beginning — hype check candidate.

Animal data on NAD+ restoration is genuinely exciting, but human longevity evidence remains thin — this is a hype check candidate.

The famous 'red wine molecule' has disappointing human translational evidence despite decades of hype — a classic case of animal data not panning out.

An autophagy-promoting polyamine with promising epidemiological links to longevity, but interventional human evidence is still early-stage.